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Anhydrotetracycline hydrochloride

CAS No. 13803-65-1

Anhydrotetracycline hydrochloride ( —— )

Catalog No. M27420 CAS No. 13803-65-1

Anhydrotetracycline (hydrochloride) is a potent competitive inhibitor of broad-spectrum tetracycline destructase enzymes.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Anhydrotetracycline hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Anhydrotetracycline (hydrochloride) is a potent competitive inhibitor of broad-spectrum tetracycline destructase enzymes.
  • Description
    Anhydrotetracycline (hydrochloride) is a potent competitive inhibitor of broad-spectrum tetracycline destructase enzymes.(In Vitro):Anhydrotetracycline (hydrochloride), a tetracycline biosynthetic precursor, inhibited Tet50, TetX, TetX-3 degradations of tetracyclines with the IC50s of 210 μM, 41 μM and 3 μM,respectively. Anhydrotetracycline (hydrochloride) inhibited Tet50, TetX, TetX-3 degradations of demeclocycline with the IC50s of 120 μM, 41 μM, 7 μM,respectively. Anhydrotetracycline (hydrochloride) inhibited Tet50, TetX, TetX-3 degradations of chlortetracycline with the IC50s of 210 μM, 75 μM, 26 μM,respectively.
  • Synonyms
    ——
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    13803-65-1
  • Formula Weight
    462.9
  • Molecular Formula
    C22H23ClN2O7
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C(C(C1=O)=C(O)C(N(C)C)C2CC3=C(C(C21O)=O)C(O)=C4C(O)=CC=CC4=C3C)N.[H]Cl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Yang XH, et al. Ultra-high performance liquid chromatography coupled with quadrupole/time of flight mass spectrometry based chemical profiling approach for the holistic quality control of complex Kang-Jing formula preparations. J Pharm Biomed Anal. 2016 May 30;124:319-36.
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