Anhydrotetracycline hydrochloride

Research use only, not for human use.

Anhydrotetracycline (hydrochloride) is a potent competitive inhibitor of broad-spectrum tetracycline destructase enzymes.

Anhydrotetracycline (hydrochloride) is a potent competitive inhibitor of broad-spectrum tetracycline destructase enzymes.(In Vitro):Anhydrotetracycline (hydrochloride), a tetracycline biosynthetic precursor, inhibited Tet50, TetX, TetX-3 degradations of tetracyclines with the IC50s of 210 μM, 41 μM and 3 μM,respectively. Anhydrotetracycline (hydrochloride) inhibited Tet50, TetX, TetX-3 degradations of demeclocycline with the IC50s of 120 μM, 41 μM, 7 μM,respectively. Anhydrotetracycline (hydrochloride) inhibited Tet50, TetX, TetX-3 degradations of chlortetracycline with the IC50s of 210 μM, 75 μM, 26 μM,respectively.

——

GPCR/G Protein

Antibacterial

——

——

——

13803-65-1

462.9

C22H23ClN2O7

>98% (HPLC)

——

O=C(C(C1=O)=C(O)C(N(C)C)C2CC3=C(C(C21O)=O)C(O)=C4C(O)=CC=CC4=C3C)N.[H]Cl

——

(-20℃)

With Ice Pack

≥ 2 years